|
|
Corgi
| SIGNALMENT: |
12-year-old,
neutered male Corgi |
| |
|
| HISTORY: |
Progressive facial
swelling for 2 months (initially unilateral, then bilateral) despite
antibiotics (amoxicillin, then enrofloxacin),
associated with emergent nasal stertor and
protrusion of the tongue |
| |
|
| PHYSICAL EXAM: |
The patient was
quiet, alert, responsive and hydrated. His temperature, pulse and
respiration were normal. Severe generalized, bilateral facial and jaw
swelling was noted. No oropharyngeal lesions
were visible, but the jaw was malleable and generally distorted.
Auscultation of the heart and lungs revealed no significant abnormalities.
The abdominal palpation was unremarkable. The peripheral lymph nodes were
not enlarged. The neurologic exam and remainder
of the orthopedic exam were within normal limits. |
| |
|
| DIAGNOSTICS: |
- CBC
- Biochemistry panel
- Urinalysis
- Skull radiographs
- Thoracic radiographs
- Abdominal radiographs
- Fine needle aspirates of maxillary bone |
|
CBC |
|
|
|
| WBC |
9.0 |
K/uL |
6.0-17.0 |
| RBC |
4.64 L |
M/uL |
5.50-8.50 |
| HGB |
10.4 L |
g/dl |
12.0-18.0 |
| HCT |
32.2 L |
% |
37.0-55.0 |
| MCV |
70 |
fL |
60-77 |
| MCH |
22.5 |
pg |
19.0-25.0 |
| MCHC |
32.4 |
% |
32.0-36.0 |
| Platelet count |
424 |
K/uL |
200-500 |
| |
|
|
|
|
Differential: |
|
|
|
| BASO |
10> |
>/ul |
0-500 |
| EOS |
500 |
/ul |
0-1250 |
| POLYS |
7450 |
/ul |
3600-11500 |
| LYMPH |
770 |
/ul |
1000-4800 |
| MONOS |
310 |
/ul |
150-1350 |
| |
|
|
|
|
RBC Morphology |
Normal |
|
|
| |
|
|
|
|
Chemistry screen |
|
|
|
| Glucose, Serum |
91 |
mg/dl |
65-130 |
| BUN |
121 H |
mg/dl |
6-29 |
| Creatinine |
5.8 VH |
mg/dl |
0.6-1.6 |
| Sodium |
152 |
meq/l |
140-158 |
| Potassium |
4.8 |
meq/l |
4.0-5.7 |
|
Sodium/Potassium Ratio |
32 |
|
27-40 |
| Chloride |
109 |
meq/l |
100-115 |
| Carbon Dioxide |
11 VL |
meq/l |
18-26 |
| Anion Gap |
32 H |
|
13-25 |
| Calcium |
13.3
H |
mg/dl |
8.0-12.0 |
| Phosphorus |
12.1 H |
mg/dl |
3.0-7.0 |
| Osmolality,
Calculated |
>340
H |
|
270-310 |
| Total protein |
6.1 |
g/dl |
5.4-7.6 |
| Albumin |
3.6 |
g/dl |
2.3-4.0 |
| Globulin |
2.5 L |
g/dl |
2.7-4.4 |
|
Albumin/Globulin Ratio |
1.4 H |
|
0.6-1.2 |
| Bilirubin,
Total |
0.1 |
mg/dl |
0.0-0.5 |
| Alkaline
phosphatase |
261 H |
U/L |
10-84 |
| ALT |
187 H |
U/L |
5-65 |
| AST |
47 |
U/L |
16-60 |
| Gamma
gt |
8 |
U/L |
2-10 |
|
Cholesterol |
251 |
mg/dl |
150-275 |
| Urinalysis: |
Specific
gravity=1.010, no other significant abnormalities reported. |
| |
|
| Radiographs: |
Skull radiographs
revealed overall decreased bone density. The normal
trabecular pattern of the skull bones was lost. The teeth appeared
prominently because of the neighboring loss of density in the skull bones
(“floating teeth”). Soft tissue swelling was noted around the maxilla.
Thoracic radiographs were within normal limits. Abdominal radiographs
revealed bilaterally small kidneys, but no other significant abnormalities. |
| |
|
| Cytology: |
See
Figure 1. (Note: Requires Adobe Acrobat
Reader)
Many morphologically normal osteoclasts
and fewer fibroblasts and osteoblasts were
visualized. |
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|
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